Resveratrol, a natural phenol found in red wine and cocoa, has been long touted by TV doctors as a "must have" supplement and according to the research, those doctors are right.
The benefits of using resveratrol include
- Lowering inflammation,
- Improving endothelial dysfunction,
- Reducing oxidative stress and can
- Preventing heart disease, stroke , anti-cancer,and type-2 diabetes.
- Acting as an anti-oxidant that aids in the removal of free radicals caused by stress, poor aging and intense exercise.
Resveratrol and Anti-Aging
Bloggers like to say that resveratrol mimetics “caloric restriction” since it activates the sirtuin 1 gene in mice studies. SIRT 1 extension, according to research, prolongs life span of both animal and humans. Studies in humans and caloric restriction show elevated longevity genes when total calories are decreased. Now does that benefit come from a drop in calories or increased weight loss?
A recent study in the European Journal of Cell Biology shows that resveratrol may increase muscle mass since, in studies, SIRT1 activation increases skeletal muscle cell proliferation. What that means is that it can help to create new muscle cells. While this is far from proven, it might warrant the need for tinkering with some resveratrol supplementation post workout.
Recent research has also linked resveratrol to potentially increasing testosterone levels while also reducing estrogen. A specific study shows that resveratrol increased blood levels of testosterone by over 50% in animals. Granted it’s in animals and it's blood levels we’re talking about but the evidence is there to do more research. What may be more impactful and meaningful right now is how resveratrol inhibits aromatase, an enzymes that increases testosterone conversion to estrogen.
So maybe resveratrol never boosts testosterone directly but instead helps to keep MORE of the testosterone that we already make around. That’s a great way to boost a physique and performance.
Resveratrol and inflammation.
We know, due to mounds of research, that excessive and out of control inflammation is terrible for our physique, performance and longevity. Our goal is to manage inflammation but not crush it, as a tiny amount of inflammation is needed for muscle growth. Resverastrol has been shown in studies to reduce one of the bigger inflammatory pathways, Nf-KB. Though it does not completely blunt the inflammatory response and actually helps to decrease exercise induced muscle damage and may increase muscle repair.
Resveratrol and endurance
A 2012 Canadian study showed that resveratrol supplementation may increase endurance, oxidative metabolism and cardiac function. The group that performed endurance training while taking resverastrol saw an increase in performance of 21%. Pretty cool.
As mentioned above, resveratrol may prevent heart disease and this was further backed up by a Canadian study that found resveratrol significantly reduced the risk of developing artherosclertic disease by 30%.
Resveratrol and cancer
A French study found that resveratrol was able to slow down both the production of and spread of cancerous cells. Though the resveratrol content came from foods such as blueberries and red wine. While there's mounds of evidence on resveratrol and cancer studies, generally, resveratrol seems to have a positive association with reducing markers of cancer.
Resveratrol and eyesight
Vision loss is a normal part of aging but resveratrol may be able to slow that down as well. Resveratrol can regulate angiogenesis and prevent the overgrowth of blood vessels that decrease eye health.
Resveratrol and memory
A UK study in 22 healthy adults found that brain blood flow was increased following resveratrol supplementation. This was backed up by a Illinois research that found mice given resveratrol had better memory function.
How Much Resveratrol Should You Take?
The Physique Formula Resveratrol contains 200 mg's of the most studied version of resveratrol, trans-resveratrol. As a result, I typically suggest that you take one capsule twice per day, with or without, meals.